Description
Trifluoromethylphenylpiperazine
Product information
IUPAC-name 1-[3-(trifluoromethyl)phenyl]piperazine
Synonyms Trifluoromethylphenylpiperazine, 3-Trifluoromethylphenylpiperazine, TFMPP
Formal name 1-
Cas number 15532-75-9, 76835-14-8 (dihydro
Formula C11H13F3N2 • 2HCl, C11H13F3N,
Molar Mass 230.234 g·mol−1
Purity 99.0 % min.
Formulations A neat solid, Powder
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): 10 mg/ml
Trifluoromethylphenylpiperazine, 3-Trifluoromethylphenylpiperazine, TFMPP, 1-(m-Trifluoromethylphenyl)piperazine, 1-(meta-Trifluoromethylphenyl)piperazine
Trifluoromethylphenylpiperazine, also known as TFMPP, is a recreational drug that is often combined with other drugs such as BZP. It is sometimes used as an alternative to the illegal substance ecstasy.
Although TFMPP is commonly used as a combination drug, it can also cause aversive effects in animals. This could explain why the DEA decided not to classify it as a controlled substance. Co-administered with BZP, it can also help release dopamine and norepinephrine.
The combination of BZP and TFMPP can also cause aversive effects in animals due to the increased levels of serotonin, dopamine, and norepinephrine. This mixture of drugs can also mimic the effects of MDMA.
Pharmacology
The 5-HT1A, 5-HT1B, and 5-HT1D receptors are known to have a strong affinity for the TFMPP. It can act as a partial agonist at all sites, except for the 5-HT2A receptor, where it is a weak antagonist.
Unlike the chlorophenylpiperazine compound, the TFMPP has little effect on the 5-HT3 receptor. It also binds to the SERT and activates the serotonin receptor. It does not affect the effects of other drugs, such as norepinephrine and dopamine.
The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.
WARNING This product is not for human or veterinary use.
This product is only available to persons of 21 years old and above.
Hazard statement(s)
| H302 | Harmful if swallowed |
| H315 | Causes skin irritation |
| H319 | Causes serious eye irritation |
| H332 | Harmful if inhaled |
| H335 | cause respiratory irritation |
| H336 | cause drowsiness or dizziness |
| Precautionary statement(s) | |
| P264 | Wash hands thoroughly after handling |
| P280 | protective gloves/protective clothing/eye protection/face protection |
| P305 + P351 + P338 | IF IN EYES: Rinse cautiously with for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P337 + P313 | If eye irritation persists: Get medical advice/attention |
| P261 | Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray |
| P271 | Use only outdoors or in a well-ventilated area |
| P304 + P340 | IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing |
| P312 | Call a POISON CENTER or doctor/physician if you feel unwell |
| P403 + P233 | Store in a well-ventilated place. Keep container tightly closed |
| P405 | Store locked up |
| P501 | Dispose of contents/container to a licensed disposal company |
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