Description

Product information

IUPAC-name   N-Ethyl-1-(3-methoxyphenyl)cyclohexan-1-amine

Synonyms     3-MeO-PCE, 3-Methoxyeticyclidine

Formal name  N-ethyl-1-(3-methoxyphenyl)-cyclohexanamine

Cas number  1364933-80-1

Formula    C₁₅H₂₃NO

Molar Mass   233.355 g·mol⁻¹

Purity     99.0 % min.

Formulations    A neat solid, Powder

3-MeO-PCE, 3-Methoxyeticyclidine

A type of dissociative anesthetic known as 3-Methoxyeticyclidine (3-MeO-PCE) is commonly sold as a designer drug. It is similar to PCP and PCE in terms of its effects.

In October 2012, an advisory council in the UK released a report about the effects of methoxetamine, which stated that the drug’s harm is comparable to that of Class B drugs under the Misuse of Drugs Act. It also suggested that other analogues of the drug should be added to the list of class B drugs. Among the other substances mentioned in the report was 3-MeO-PCE.

The report also discussed the receptor binding properties of different dissociatives, such as 3-MeO-PCE, 4-MeO-PCP, and 3-MeO-PCP. These properties showed that they have a significant affinity for the receptor site of the NMDA.

The Ki values of 3-MeO-PCE for different receptors, such as the dopamine transporter and the serotonin transporter, were reported. These properties show that the drug has a significant binding potential to the 1 and 2 receptors.

Chemistry

Arylcyclohexylamines, such as 3-MeO-PCE, are commonly referred to as arylcyclohexylamine drugs. These drugs have structures that include a cyclohexane ring and an aromatic ring. The amine group and the phenyl ring are respectively bound to an aromatic and cyclohexane ring.

Like other arylcyclohexylamines, 3-MeO-PCE is also bound to the same carbon of the cyclohexanone ring. However, instead of an amino methyl chain, it has an ethyl chain instead. This is similar to the structure of the drug known as MXE, but it lacks the R2 substituted ketones.

Pharmacology

The 3-MeO-PCE is a protein that targets the receptor for the neuromodulator known as NMDA. This receptor allows electrical signals to pass between the spinal column and the brain. When the receptor is closed, the signals are not able to reach the neurons. This results in the disconnection of the neurons, which can lead to various symptoms such as difficulty moving and feeling.

The Ki values of the 3-MeO-PCE protein are 61 nM for the neurotransmitter NMDA receptor, 743 for the dopamine transporter, and 2097 for the histamine H2 receptor. It also targets the alpha-2A adrenergic receptor, the serotonin transporter, and the 1 receptor.

The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.

Hazard statement(s)