Description
Ketamine
Product information
IUPAC (RS)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
Synonyms Ketalar
CAS 6740-88-1
Formula C13H16ClNO
Molecular Mass. 237.73 g·mol−1
Purity 99.0 % min.
Formulations A neat solid, Powder
Solubility
- DMF: Slightly soluble
- DMSO: Slightly soluble
- Ethanol: Slightly soluble
- PBS (pH 7.2): 3 mg/ml
Ketamine
In addition to being used for the maintenance and induction of anesthesia, ketamine is also used for treating depression and other pain conditions. In 1962, a new compound was developed that is derived from phencyclidine.
Ketamine can induce a state of dissociation, which is characterized by amnesia, pain relief, and sedation. Its distinctive features include the preservation of airway reflexes and breathing, as well as the stimulation of heart function with bronchodilation and increased blood pressure.
Although it can be used for treating depression, the effects of ketamine on a single dose can wane over time. Because of this, it is not yet known if repeated use can have long-term effects.
Regular users of the drug have reportedly experienced toxic effects, such as kidney and liver toxicity. The main mechanism by which this drug works is the NMDA receptor.
The drug was first synthesized in 1962. It was approved for use in the US in 1970. It has been used in various medical fields, such as veterinary medicine, and it was also used during the Vietnam War as an anesthetic. Currently, ketamine is on the WHO’s list of essential medicines.
WARNING This product is not for human or veterinary use.
This product is only available to persons of 21 years old and above.
Hazard statement(s)
| H302 | Harmful if swallowed |
| H315 | Causes skin irritation |
| H319 | Causes serious eye irritation |
| H332 | Harmful if inhaled |
| H335 | cause respiratory irritation |
| H336 | cause drowsiness or dizziness |
| Precautionary statement(s) | |
| P264 | Wash hands thoroughly after handling |
| P280 | protective gloves/protective clothing/eye protection/face protection |
| P305 + P351 + P338 | IF IN EYES: Rinse cautiously with for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P337 + P313 | If eye irritation persists: Get medical advice/attention |
| P261 | Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray |
| P271 | Use only outdoors or in a well-ventilated area |
| P304 + P340 | IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing |
| P312 | Call a POISON CENTER or doctor/physician if you feel unwell |
| P403 + P233 | Store in a well-ventilated place. Keep container tightly closed |
| P405 | Store locked up |
| P501 | Dispose of contents/container to a licensed disposal company |
Reviews
There are no reviews yet.