Description
Methoxphenidine
Product information
IUPAC-name (±)-1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine
Synonyms 2-Methyl MAF, 2-MeO-Diphenidine, MXP, Methoxydiphenidine
Formal name 1-
Cas number 127529-46-8
Formula C20H25NO
Molar Mass 295.426 g·mol−1
Formulation Powder
Solubility
- DMF: 50 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- PBS (pH 7.2): 3 mg/ml
Shipping & Storage Information
Methoxphenidine is a dissociative compound under the diarylethylamine family. It was widely used as a treatment for neurotoxic injury. As an homeomorph of MK-801 and arylcyclohexylamines, it can act as an NMDA receptor channel blocker which can lead to neuroprotective and dissociative effects. As an analog of diphenidine, it features a methoxy group at the two positions of a phenyl group.
Methoxphenidine is a type of diarylethylamine that has been studied as a neurotoxic treatment. It was first marketed as a replacement for the popular drug methoxetamine in the US in 2013. Despite the lack of evidence it produces similar effects, it was still sold as a replacement for MXE. Methoxphenidine is a designer drug that has been developed to mimic the structural and functional features of other substances.
Chemistry
Methoxphenidine is a dissociative class of compounds that has the same chemical structure as phenethylamine. Its terminal amino group is incorporated into a phenyl ring. Its chemical structure consists of a phenyl ring and a substituted phenethylamine.
Pharmacology
MXP is an NMDA receptor antagonist that works by closing the NMDA receptors. When the receptor is blocked, the neurons are disconnected from the brain and spinal column. This impairs the ability to feel and move.
The toxicological and physiological properties of this compound have not been analyzed. Usage of this Chemical should be for research and forensic purposes only.
WARNING This product is not for human or veterinary use.
This product is only available to persons of 21 years old and above.
Hazard statement(s)
| H302 | Harmful if swallowed |
| H315 | Causes skin irritation |
| H319 | Causes serious eye irritation |
| H332 | Harmful if inhaled |
| H335 | May cause respiratory irritation |
| H336 | May cause drowsiness or dizziness |
| Precautionary statement(s) | |
| P264 | Wash hands thoroughly after handling |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection |
| P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P337 + P313 | If eye irritation persists: Get medical advice/attention |
| P261 | Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray |
| P271 | Use only outdoors or in a well-ventilated area |
| P304 + P340 | IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing |
| P312 | Call a POISON CENTER or doctor/physician if you feel unwell |
| P403 + P233 | Store in a well-ventilated place. Keep container tightly closed |
| P405 | Store locked up |
| P501 | Dispose of contents/container to a licensed disposal company |
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