What Are Ketamines?

Ketamine is a pharmaceutical drug mostly used for initiating and sustaining anesthesia. It causes sedation, a dissociative anesthetic, and amnesia, giving pain relief (1). Ketamine is sometimes mixed with other drugs such as midazolam and can be used to prevent and relieve adverse reactions to anesthesia. Although ketamine can have severe side effects such as respiratory depression, seizures, coma, respiratory blockage, hallucinations, and aggressive behavior, it has a number of benefits. It is frequently prescribed for patients with certain disorders or who have chronic pain.

Ketamine abuse is characterized by excessive drug use, frequent parties, injecting at-home or in public, lying to friends and family, taking large amounts of alcohol, and using the drug to get high. Ketamine use can be risky, especially if you’re not familiar with the side effects. Side effects of ketamine can range from high fever to seizures and even death. Some other minor side effects include headache, runny nose, itching or watering of the eyes, dry mouth, increased heart rate, anxiety, agitation, diarrhea, dizziness, constipation, impaired vision, and chest pain. Ketamine abuse is often associated with a number of serious health risks including infection, dehydration, electrolyte imbalance, and coma (2).


Some Known Side Effects

Depression, anxiety, psychosis, mania, and hallucinations are some of the more serious side effects associated with ketamine use (3). While ketamine infusions are being used less due to negative side effects, there are still some precautions that should be taken when using this recreational drug. Anyone who has experienced the effects of ketamine should seek medical attention immediately. Before considering ketamine injections, medical consultation should be sought for any other conditions, diseases, or medications.

Although ketamine has been shown to be safe when administered under proper medical supervision, some side effects may cause long-term effects. Some individuals experience euphoria, anxiety, and depression when taking these drugs. People who take them long-term may have problems sleeping, and their hallucinations can affect their judgment. These feelings generally go away once the person begins to get used to their new found feeling of well-being. However, because of the long-term effects of ketamine, individuals should work closely with their primary care physicians and a psychologist to monitor their mental health. As the body adjusts to the effects of the drug, long-term safety should be the main concern.

Ketamine Usage

Ketamines are commonly used as a source of relief from pain because of how effective they are at reducing pain (4). They are effective in the reduction of pain, but the use of ketamine for long periods of time could potentially lead to an addiction. Because of how addictive these drugs are. Those who use them on a regular basis may find it very difficult to stop using them on their own. Long-term use of ketamine could lead to serious problems.


Another reason why individuals turn to ketamine-based drugs for chronic pain is because these drugs are readily available and don’t require a prescription. This allows people to buy the drug whenever they need it. Because of how easy to obtain and use these drugs, ketamine use can easily lead to addiction. Those who become dependent on the drug may not be able to stop taking it on their own, and will often require outside help in order to break their habit. If an individual does not receive adequate support, they could have serious mental health issues (5).

There is one type of ketamine that acts in a different way than other drugs in which it acts in the brain’s NMDA receptor. When the NMDA is activated, the brain produces a chemical known as glutamate, which is responsible for the feeling of pleasure associated with consuming glutamate. However, when the NMDA is accidentally blocked, ketamines act in much the same manner.

While the recreational use of ketamine has been established, there are also some serious side effects associated with their use. The most common side effect is a rapid increase in blood pressure. This can be a dangerous side effect if the individual who uses ketamine becomes dehydrated. If this occurs, the individual may become unconscious and be unable to breathe properly. Ketamines are very powerful medications and should be used with extreme care.