Description

Product information

IUPAC-name    1-(3-chlorophenyl)piperazine

Synonyms     3-Chlorophenylpiperazine, meta-Chlorophenylpiperazine, 1-(m-Chlorophenyl)piperazine, 3-CPP, mCPP

Formal name  1-(3-chlorophenyl)-piperazine, monohydrochloride

Cas number   6640-24-0, 13078-15-4 HCI

Formula    C₁₀H₁₃ClN₂, C₁₀H₁₃ClN₂ • HCl

Molar Mass   196.68 g·mol⁻¹

Purity     99.0 % min.

Formulations    A neat solid, Powder

3-Chlorophenylpiperazine, meta-Chlorophenylpiperazine, 1-(m-Chlorophenyl)piperazine, 3-CPP, mCPP

The psychoactive substance meta-Chlorophenylpiperazine, also known as mCPP, was developed during the 1970s and was used in scientific research before it was eventually marketed as a designer drug during the 2000s. It has been found in various pills marketed as “ecstasy” in the US and Europe.

Contrary to its recreational use, mCPP is not preferred by drug users. It can cause various effects, such as anxiety and depression, and it can also trigger panic attacks in people. It can also worsen the symptoms of obsessive-compulsive disorder in people. Although it doesn’t have any reinforcing effects, it can also stimulate the production of various psychostimulants and hallucinogenic compounds.

It can also cause headaches in people, and it has been used in the testing of various anti-migraine drugs. It can also stimulate the production of anorectic compounds, which has led to the development of new treatment options for obese individuals.

Pharmacology

mCPP has a significant amount of affinity for various serotonin receptors, such as the 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT2A. It also has an interest in the 2-adrenergic, H1, I1, and NET receptors. It has also been shown to act as a serotonin releasing agent.

Its most effective action is at the 5-HT2B and 5-HT2C receptors. These two receptors are responsible for the negative effects of mCPP, such as appetite loss and anxiety. It can also cause various other effects, such as hypoactivity and penile erection. The latter two are likely triggered by 5-HT3 stimulation.

mCPP has a 10-fold selectivity for the 5-HT2C receptor compared to the 5-HT2B and 5-HT2A receptors. It is also an antagonist of these two receptors. In studies, it has been shown that mCPP can be useful as a partial agonist of these two receptors.

The metabolism of mCPP is performed through the activation of the para-hydroxy-mCPP by the CYP2D6 isoenzyme. The half-life of this drug is approximately 4 to 14 hours.

mCPP is a derivative of various piperazine drugs, such as trazodone, etoperidone, enoxazodone, mepiprazole, cloperidone, and peraclopone. It can be formed by dealkylation via the CYP3A4 enzyme. In order to minimize the effects of these drugs on the body, it should be taken with caution when combined with other drugs that are known to increase the concentration of the parent compound.

The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.

Hazard statement(s)