Description

6-(2-Aminopropyl)-2,3-dihydrobenzofuran

Product information

IUPAC-name   1-(2,3-dihydro-1-benzofuran-6-yl)propan-2-amine

Synonyms        6-APDB, 6-(2-Aminopropyl)-2,3-dihydrobenzofuran, EMA-3, 4-desoxy-MDA

Formal name     2,3-dihydro-α-methyl-6-benzofuranethanamine

Cas number    152623-93-3

Formula            C₁₁H₁₅NO

Molar Mass     177.247 g·mol⁻¹

Formulation      Powder

6-APDB, also known as 6-(2-Aminopropyl)-2,3-dihydrobenzofuran, EMA-3, 4-desoxy-MDA is an analog of the hallucinogenic compound MDA and 6-APB. This compound completely fill in for the entactogen MBDB in creature drug-separation studies and squares the reuptake of serotonin (IC50 = 322 nM) more intensely than dopamine and norepinephrine (IC50s = 1,997 and 980 nM, separately) by rodent synaptosomes.

6-APDB is a research chemical that is commonly used as a stimulant and an entactogenic compound. It is a relative analogue of 6-APB, a cyclic analogue of the phenylalanine-MDA and can be commonly used for the treatment of serotonin-dependent behavioral problems. It exhibits the same properties as entactogenic or serotonin-selective releasers.

6-APDB was first discovered in 1993 along with 5-APDB. It was initially considered a non-toxic alternative to MDMA. It was only used for research purposes.

Chemistry

6-APDB is a member of the benzofuran family and is bound to an amino acid. It exhibits a phenethylamine core and a methyl chain. 6-APDB does not have a methyl substitution. This is an analogue of MDA, where the 4-cyclic oxygen is replaced with a methylene dioxy bridge.

Pharmacology

6-APDB is a triple reuptake inhibitor that activates the release of the monoamine neurotransmitters serotonin and dopamine. These chemicals play a vital role in the brain’s ability to feel motivated and focused. This process promotes the release of the neurotransmitters by preventing them from reabsorption and retention. It allows them to accumulate in the brain and render them liable to be reused.

6-APB is an unsaturated benzofuran derivative that has been known to have pharmacological effects.

Not much is known about the pharmacological and toxicological properties of 6-APB. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.

Hazard statement(s)