Description

Product information

IUPAC  2-(2-(4-butoxybenzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)-N,N-diethylethan-1-amine

Synonyms  Butonitazene, Butoxynitazene

Formal Name  2-[(4-butoxyphenyl)methyl]-N,N-diethyl-5-nitro-1H-benzimidazole-1-ethanamine

CAS    95810-54-1

Formula   C₂₄H₃₂N₄O₃

Molecular Weight  424.55 g·mol⁻¹

Purity     99.0 % min.

Formulations    A neat solid, Powder

Butonitazene, Butoxynitazene

Butonitazene, a novel opioid, is structurally different from fentanyl. It has been reported that these drugs can cause psychoactive effects similar to that of heroin and other opioid drugs. However, these drugs also have negative effects, such as death. Similar compounds are Metonitazene, etonitazene, and isotonitazene.

The benzimidazole class is thought to act as a semi-rigid analogue of fentanyl. Using large-scale opioid receptor ligand analysis, this template identified mu-specific areas on opioid receptors. It matches a separate mu-specific region, while sharing a small area with the fentanyl class. However, it is unclear whether Butonitazene is a legitimate analgesic.

The first known synthetic opioids were synthesized during the 1950s. According to data, these drugs can have a potency that is similar to or greater than that of fentanyl. Butonitazene is not currently scheduled for the US market. Other drugs such as metonitazene and isotonitazene are also considered Schedule I substances.

A class of substances known as benzimidazole rings is composed of an ethylamine and a benzyl group at its 1- and 2-positions. Small structural modifications can allow for the production of various analogous compounds.

Pre-clinical studies show that benzimidazole-opioids have similar properties to those of other mu-opioid receptor agonists. These compounds exhibited strong analgesic effects when compared with morphine. In a study conducted on rodents, several different compounds, such as butonitazene, etonitazepyne, flunitazene, and metonitazene, exhibited varying potencies.

Compared to morphine, flunitazene, etonitazepyne, and metonitazene are more potent analgesics. In vitro studies also revealed that these compounds, along with other mu-opioid receptor agonists, bind to and activate the mu-opioid receptor. These compounds, which are similar to fentanyl and morphine, act as mu-opioid receptor agonists.

The activation of the mu-opioid receptor by different compounds, such as butonitazene, metonitazene, and protonitazene, has been linked to adverse effects of opioid analgesics. It is also known that these compounds can cause respiratory depression and arrest.

In the US, the abuse of these compounds has led to the positive identification of several benzimidazole-opioids in various toxicological cases.

The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.

Hazard statement(s)