LSZ

$330.00$5,480.00

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Description

LSZ, Lysergic acid 2,4-dimethylazetidide, LA-SS-Az

Product information

IUPAC-name   [(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-[(2S,4S)-2,4-dimethylazetidin-1-yl]methanone

Synonyms     LSZ, Lysergic acid 2,4-dimethylazetidide, LA-SS-Az, Diazedine, Lambda

Formal name  [(6aR,9R)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-[(2S,4S)-2,4-dimethylazetidin-1-yl]methanone

Cas number    470666-31-0

Formula    C21H25N3O

Molar Mass   335.451 g·mol−1

Purity     99.0 % min.

Formulations    A neat solid, Powder

Appearance      Crystalline Solid, Powder

Solubility    

  • DMF: 10 mg/ml
  • DMF:PBS (pH 7.2) (1:7): 0.12 mg/ml
  • DMSO: 1 mg/ml
  • Ethanol: 1 mg/ml
Shipping & Storage Information
Storage  -20°C
Shipping  Room Temperature in continental US; vary elsewhere
Stability   ≥ 2 years

LSZ, Lysergic acid 2,4-dimethylazetidide, LA-SS-Az, Diazedine, Lambda

A class of drugs known as LSD analogue, which is also known as LSZ, was developed by David Nichols and his team at Purdue University. A synthetic LSD-like substance known as 2,4-dimethylazetidide is produced by the lysergamide chemical class. It can produce psychedelic effects when ingested. It was made with the diethylamide group bound into azetidine rings. There are three stereoisomers around this region, and the most potent one is the (S,S,+), which is slightly more potent than LSD in drug discrimination tests.

There have been several reports of illicit laboratories producing lysergic acid 2,4 diethylazetidide. These drugs were reportedly being distributed in liquid form or on blotter paper.

In 2013, LSZ was seen on the UK’s designer chemical and pharmaceutical markets. It then gained widespread popularity through mail-order psychedelic shops in 2012.

Prior to 2012, LSZ had no known human usage. It was first spotted in the UK in 2012 and became popular through a cluster of mail-order novel shops. There have also been various reports of it being produced in illicit laboratories and being distributed in liquid solution or blotter paper.

Although it is not considered to be addictive, it can cause severe psychological reactions, such as paranoia and anxiety, especially among those with mental disorders. It is important to avoid using this substance in combination with other drugs or in combination with other harmful substances.

Chemistry

Lysergic acid 2,4 diethylazidide, or LSZ, is a semi-synthetic alkaloid of lysergamide. It has a core structure that is composed of amine functional groups bound to the RN chemical structure. This polycyclic structure has multiple phenethylamine and tryptamine groups.

The structure is composed of a bicyclic hexahydroindole and a bicyclic quinoline group. When the carbon 8 of the quinoline reaches the point where an amide group is bound, it forms a 2,4 dimethylazetidide compound. LSZ is then substituted with a methyl group.

There are three stereoisomers around the azettidine ring, and the most active one is the isomer of LSD. It is more potent than LSD in drug discrimination tests.

Pharmacology

The drug LSZ is a partial agonist of 5-HT2A. It is believed that the effects of this drug can trigger a psychedelic experience. However, the exact mechanism by which this happens remains unclear.

The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.

WARNING This product is not for human or veterinary use.

This product is only available to persons of 21 years old and above.
Hazard statement(s)
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 cause respiratory irritation
H336 cause drowsiness or dizziness
Precautionary statement(s)
P264 Wash hands thoroughly after handling
P280 protective gloves/protective clothing/eye protection/face protection
P305 + P351 + P338 IF IN EYES: Rinse cautiously with for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337 + P313 If eye irritation persists: Get medical advice/attention
P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray
P271 Use only outdoors or in a well-ventilated area
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P312 Call a POISON CENTER or doctor/physician if you feel unwell
P403 + P233 Store in a well-ventilated place. Keep container tightly closed
P405 Store locked up
P501 Dispose of contents/container to a licensed disposal company

Additional information

Weight

10g, 25g, 50g, 100g, 250g, 500g, 1000g

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